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HONG KONG, March 6, 2026 - (ACN Newswire via SeaPRwire.com) – Hong Kong Trade Development Council (HKTDC), in collaboration with Hong Kong Science and Technology Parks Corporation (HKSTP), led a delegation of 20 local innovation and technology (I&T) companies and institutions to Barcelona, Spain, concluding a highly successful participation at the world’s premier connectivity event—Mobile World Congress (MWC), and debuted at the startup-centric stage—4 Years From Now (4YFN) 2026. This participation has enabled local tech firms to access markets overseas, showcasing their strengths in research and development (R&D), and demonstrating the city’s role as a leading international I&T hub.The delegation effectively spotlighted Hong Kong’s cutting-edge innovative solutions in Connectivity, Devices and Systems, Digital Transformation, and support from Ecosystem Partners, successfully engaged global industry leaders and investors to generate business collaboration, technology co-development and investment opportunities.Iris Wong, Director, Merchandise Trade and Innovation / Director, External Relations, HKTDC, said, “Hong Kong is committed to developing into an international I&T centre, actively promoting cross-industry integration and driving high-quality development of the industries through technological innovation. We possess a robust mobile communications infrastructure, and the industry is highly competitive in research and development as well as technology related to 5G/6G applications and AI integration. This year, the Hong Kong Tech Pavilion adopts a dual-pavilion layout to showcase the city's I&T capabilities on two international platforms – MWC and 4YFN – helping the industry expand into European and broader global business opportunities.”Derek Chim, Head of Startup Ecosystem and Development, HKSTP said, “MWC and 4YFN bring together the world’s most influential stakeholders across connectivity and innovation ecosystems. Our dual-zone presence gave our innovators the global stage to validate solutions, gain visibility and drive business traction. HKSTP will continue to strengthen the I&T ecosystem and bring Hong Kong's research excellence to Europe and beyond.”A series of dialogues and exchanges—spanning networking reception and themed talks to pitching sessions—were held at the Pavilions and attracted an enthusiastic response. The events highlighted the dynamism of Hong Kong’s I&T ecosystem to European audiences, while enabling participants to more deeply understand the city’s unique advantages as a “super-connector” and “super value-adder”. This positions the city as a strategic springboard for international companies entering Asian markets, while enabling local and Chinese Mainland firms to leverage this edge to expand globally.Following his visit to the Hong Kong Tech Pavilion, Alejandro Gallego, International Business Director of AMEC, said: “The Hong Kong Pavilions are highly inspirational, and the exhibiting companies we visited showcased exceptionally innovative technological solutions. We have started conversations with Hong Kong companies to explore concrete opportunities for collaboration.”Jacobo Pérez-Soba, Manager of the Internationalisation Department, Madrid Chamber of Commerce & Industry, said: “The solutions and services provided by Hong Kong companies are highly forward-looking and demonstrate outstanding technological advancement. I also learned about upcoming tech events in Hong Kong, which are expected to be of significant interest to Spanish companies and startups.”As 2026 marks the opening year of China’s 15th Five-Year Plan, with technological innovation as one of the national priorities, HKTDC shall continue to join hands with HKSTP to support local tech firms in "going global" through jointly organising the Hong Kong Tech Pavilion, accelerating Hong Kong’s I&T by building a vibrant, internationally competitive ecosystem and fostering the development of new quality productive forces.Photo download: https://bit.ly/3Nm5qHlHong Kong Tech Pavilion debuted a dual presence at MWC and 4YFN 2026, featuring 20 Hong Kong I&T companies and institutions in Barcelona to showcase the city’s innovative technology solutions. Throughout the four-day event, the Hong Kong Tech Pavilion at MWC saw a constant stream of visitors, attracting a significant number of international telecom operators, corporate decision-makers, and investors. The Hong Kong Tech Pavilion debuted at the startup-centric 4YFN, served as a vibrant stage for Hong Kong’s up-and-coming innovation power. A series of dialogues and exchanges—spanning networking reception and themed talks to pitching sessions—were held at the MWC Pavilion and attracted an enthusiastic response. The seminar “Ready for Asia' Take the Fast Track Through Hong Kong” was held at the Pavilion to share strategies for international companies to enter Asian markets, speakers included (starts from the second left in Photo 6) Chris Lo, Regional Director, Europe, Central Asia & Israel of HKTDC; Paula Kant, Head, Investment Promotion of InvestHK; Jennifer Chan, Board Member of HKSTP; Prof Christopher Chao, Senior Vice President (Research and Innovation) of The Hong Kong Polytechnic University and Daniel Garcia, Founder of a Spain startup VirtuaBroker. Another seminar, the "Hong Kong Tech Disrupt" featured insights from Jennifer Chan, Board Member of HKSTP (first from left); Derek Chim, Head of Startup Ecosystem and Development of HKSTP (middle); alongside were representatives from park companies, including Kinson Chan, CEO of eSIX Limited (second from right) and Edward Mak, CEO & Founder of Vista InnoTech (second from left). The seminar drew attention from numerous professionals in the European technology sector.Full list of 20 tech entities showcasing at Hong Kong Tech Pavilion during MWC and 4YFN 2026:MWC 2026 – Booth 6E44 at Hall 61Entoptica LimitedDevices & Systems2eSIXConnectivity3Faraconix Technologies Co., Ltd.Connectivity4FreightAmigo Services LimitedDigital Transformation5Glassdio Scientific Company LimitedConnectivity6Harvest Elite International LimitedDigital Transformation7HongKong Umedia LimitedDevices & Systems8iASPEC Services LimitedDigital Transformation9InvestHKEcosystem Partners10Robocore Technology LimitedDevices & Systems11Shannon & Turing Technology LimitedConnectivity12The Hong Kong Polytechnic UniversityEcosystem Partners13Xeroptix TechnologyDevices & Systems4YFN 2026 – Booth 8.1B31 at Hall 8.114AIGM LimitedDigital Transformation15BWSea Technology (HK) Co., LimitedDigital Transformation16Cresento LimitedDevices & Systems17GoGoChart Technology LimitedDigital Transformation18HairCoSys LimitedDevices & Systems19KNQ Technology LimitedDigital Transformation20Vista Innotech LimitedDevices & SystemsAbout HKTDCThe Hong Kong Trade Development Council (HKTDC) is a statutory body established in 1966 to promote, assist and develop Hong Kong's trade. With over 50 offices globally, including 13 in Chinese Mainland, the HKTDC promotes Hong Kong as a two-way global investment and business hub. The HKTDC organises international exhibitions, conferences and business missions to create business opportunities for companies, particularly small and medium-sized enterprises (SMEs), in the mainland and international markets. The HKTDC also provides up-to-date market insights and product information via research reports and digital news channels.About Hong Kong Science and Technology Parks CorporationHong Kong Science and Technology Parks Corporation (HKSTP) was established in 2001 to create a thriving I&T ecosystem grooming 12 unicorns, more than 16,000 research professionals and over 2,400 technology companies from 24 countries and regions focused on developing healthtech, AI and robotics, fintech and smart city technologies, etc.Our growing innovation ecosystem offers comprehensive support to attract and nurture talent, accelerate and commercialise innovation for technology ventures, with the I&T journey built around our key locations of Hong Kong Science Park in Pak Shek Kok, InnoCentre in Kowloon Tong and three modern InnoParks in Tai Po, Tseung Kwan O and Yuen Long realising a vision of new industrialisation for Hong Kong, where sectors including advanced manufacturing, micro-electronics and biotechnology are being reimagined.Hong Kong Science Park Shenzhen Branch in Futian, Shenzhen plays positive roles in connecting the world and the mainland with our proximity, strengthening cross-border exchange to bring advantages in attracting global talent and allowing possibilities for the development of technology companies in seven key areas: Medtech, big data and AI, robotics, new materials, microelectronics, fintech and sustainability, with both dry and wet laboratories, co-working space, conference and exhibition facilities, and more.Through our R&D infrastructure, startup support and enterprise services, commercialisation and investment expertise, partnership networks and talent traction, HKSTP continues to contribute in establishing I&T as a pillar of growth for Hong Kong. More information about HKSTP is available at www.hkstp.org.Media Contact:Hong Kong Science and Technology Parks CorporationAngela Lau, +852 6535 7611, angela.lau@hkstp.orgHong Kong Trade Development CouncilWinnie Kan, +852 2584 4055, winnie.wy.kan@hktdc.org Copyright 2026 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com

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TOKYO, Mar 6, 2026 - (JCN Newswire via SeaPRwire.com) - Anime Tokyo Station is an anime exhibition site focused on Japanese anime content, which has developed a devout fan base around the world. From February 21 (Sat.) to May 24 (Sun.), 2026, it will be holding the “That Time I Got Reincarnated as a Slime” Special Exhibition. A preview was held for the press on February 20 (Fri.), the day before the exhibition opened.©Taiki Kawakami, Fuse, KODANSHA/ “Ten-Sura” ProjectThis special exhibition looks back on the story through the third season of the TV anime, highlighting iconic scenes and memorable lines. Visitors can enjoy exhibits unique to Anime Tokyo Station, including interactive digital content and a photo spot where they can take commemorative photos with Rimuru. With displays that unfold alongside character introductions and other features, even those who have not yet seen the anime can enjoy the exhibition as preparation for the film set for release in late February and the fourth season of the TV anime starting in April.Come to Anime Tokyo Station and experience the appeal of “That Time I Got Reincarnated as a Slime.”Exhibits©Taiki Kawakami, Fuse, KODANSHA/ “Ten-Sura” ProjectAbout the SeriesWhat is “That Time I Got Reincarnated as a Slime”?“That Time I Got Reincarnated as a Slime” is an isekai anime series following a protagonist who is reincarnated as a slime in another world, using the skills he acquires along with his wits and courage to gather allies. The first season of the TV anime aired on TOKYO MX and other channels from October 2018 to March 2019.In 2021, TV anime Season 2 Part 1 aired from January to March, followed by the spin-off comic adaptation “Slime Diaries: That Time I Got Reincarnated as a Slime” from April to June, and TV anime Season 2 Part 2 from July to September, making for nine consecutive months of broadcasts. Then, on November 25, 2022, “That Time I Got Reincarnated as a Slime: The Movie – Scarlet Bond” was released nationwide, becoming a major hit with over one million admissions and box office revenue of 1.4 billion yen in Japan.To commemorate the 10th anniversary of the web novel “That Time I Got Reincarnated as a Slime,” the Tensura 10th Project launched on February 20, 2023. As part of this project, the all-new three-episode animation “That Time I Got Reincarnated as a Slime: Visions of Coleus” began streaming on November 1, 2023. On December 16, 2023, the series’ first large-scale event, That Time I Got Reincarnated as a Slime: Tensura 10th Live, was held at Mori no Hall 21 in Matsudo. Furthermore, the third season of the TV anime aired from April to September 2024. Following the final episode of Season 3, production of a second theatrical film and Season 4 of the TV anime was announced. “That Time I Got Reincarnated as a Slime: The Movie – Tears of the Azure Sea” is set to release on February 27, 2026.The original manga “That Time I Got Reincarnated as a Slime” (serialized in Kodansha’s Monthly Shonen Sirius / Manga: Taiki Kawakami, Original story: Fuse, Character design: Mitz Vah) is a comic adaptation of the popular web novel of the same name by Fuse, which surpassed 1 billion page views on the user-generated novel publishing website “Shosetsuka ni Naro.” The combined worldwide circulation of the manga, novels, and spin-off works has exceeded 56 million copies (as of June 2025).* “Shosetsuka ni Naro” is a registered trademark of HinaProject Inc.Tensura Portal Site: ten-sura.comOfficial X: @ten_sura_anime / Official Instagram: tensura_official / Official TikTok: @ten_sura_animeEvent OverviewTitle:“That Time I Got Reincarnated as a Slime” Special ExhibitionDates:February 21, 2026 to May 24, 2026Name:Anime Tokyo Station (also known as "Anime Tokyo")Location:Floors B1 to 2F of Tokyu East 5 (2-25-5 Minami-Ikebukuro, Toshima-ku, Tokyo) * 4 minutes on foot from Ikebukuro StationHours:11:00 a.m. to 7:00 p.m. (last admission: 6:45 p.m. / Special exhibitions close: 6:30 p.m.)Closed:Mondays* If Monday falls on a holiday, the venue will be open on Monday and closed on the following dayNew Year's holiday periodMay be closed on other daysPlease check the venue website before coming.Admission fee:FreeWebsite:https://animetokyo.jp/en/SNS:X｜https://x.com/animetokyo_info　（@animetokyo_info）Instagram｜https://www.instagram.com/animetokyostation/（@animetokyostation）YouTube｜https://www.youtube.com/channel/UCSJOjGJE5Yiqw3PZ97AVdJwInquiries regarding this press releasePublic Relations Office of "Anime Tokyo Station" (Kyodo PR)Contact person: Miri YasudaE-mail: animetokyo-pr@kyodo-pr.co.jp Press release: https://www.acnnewswire.com/docs/files/20260306.pdf  Copyright 2026 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com

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West Palm Beach, FL, Mar 5, 2026 - (ACN Newswire via SeaPRwire.com) - U.S. Polo Assn., the official sports brand of the United States Polo Association (USPA), proudly announces the continued expansion of its Collegiate Partnership Program (CPP) for the 2026 season and academic year. Now in its eighth consecutive year, the program reaches a historic milestone by supporting 70 collegiate teams across 31 universities nationwide, the largest number of teams ever participating in the program.U.S. Polo Assn.'s Collegiate Partnership Program featuring the California Polytechnic State University Women's and Men's Polo TeamsPhoto Credit: California Polytechnic State University Polo TeamsU.S. Polo Assn. will outfit hundreds of student-athletes from coast to coast, including small private and large public institutions, Ivy League Universities, and Historically Black Colleges and Universities (HBCUs). The CPP supports 35 women's and 35 men's teams, reinforcing U.S. Polo Assn.'s long-standing commitment to growing the sport at the collegiate level. This season welcomes two new schools, Babson University and Southern Methodist University, joining a distinguished group of institutions nationwide.This year, U.S. Polo Assn. will generously provide each partnered program with custom-performance team jerseys, white performance game pants, polo shirts, caps, equipment gear bags, and exclusive USPA Pro merchandise, along with a monetary donation. The program also continues its popular collegiate social media contest, where teams have the opportunity to win additional prizes through creative digital engagement and storytelling.Participating Schools Include:Babson UniversityMorehouse CollegeTrinity UniversityUniversity of North TexasBrown UniversityOklahoma State UniversityUniversity of California - DavisUniversity of Southern CaliforniaCalifornia Polytechnic State UniversityOregon State UniversityUniversity of ConnecticutUniversity of South Carolina - AikenColorado State UniversitySkidmore CollegeUniversity of IdahoUniversity of VirginiaCornell UniversitySouthern Methodist UniversityUniversity of KentuckyUniversity of Wisconsin - MadisonGeorgetown UniversityStanford UniversityUniversity of MarylandVirginia Tech UniversityMichigan State UniversityTexas A&M UniversityUniversity of MichiganYale UniversityMontana State UniversityTexas Tech UniversityUniversity of New Hampshire "U.S. Polo Assn. is proud to support a record number of collegiate polo teams and student-athletes through the Collegiate Partnership Program," said J. Michael Prince, President and CEO of USPA Global, the company that manages the multi-billion-dollar U.S. Polo Assn. brand. "This critical program strengthens the foundation of the sport by providing meaningful resources to collegiate polo programs across the country. Supporting 70 teams this season reflects both the growth of the program and our long-term commitment to supporting the next generation of players both on and off the polo field."Enrollment for U.S. Polo Assn.'s Collegiate Partnership Program is open to all colleges and universities with a USPA-sanctioned polo team and lasts for the academic year. Collegiate polo teams compete in the Fall and Spring, with the official season running through April 2026 and culminating in the National Intercollegiate Championship (NIC)."Our partnership with U.S. Polo Assn. for the last eight years continues to make a meaningful difference for collegiate programs nationwide," said Liz Brayboy, Chair of the USPA's Intercollegiate/Interscholastic Committee. "The support provided through the Collegiate Partnership Program helps teams build stronger programs, develop student-athletes, and showcase the spirit and sportsmanship that define collegiate polo."The two-time award-winning series Breakaway, created by Global Polo, the media subsidiary of USPA Global, will feature a new episode in its upcoming season. Titled "Breakaway: Polo in College," the episode will air later this year on ESPNU, offering national exposure to the excitement and impact of collegiate polo. Check your local listings for air times.About U.S. Polo Assn. and USPA GlobalU.S. Polo Assn. is the official sports brand of the United States Polo Association (USPA), the largest association of polo clubs and polo players in the United States, founded in 1890 and located in Wellington, Florida. With a multi-billion-dollar global footprint and worldwide distribution through more than 1,200 U.S. Polo Assn. retail stores as well as thousands of additional points of distribution, U.S. Polo Assn. offers apparel, accessories, and footwear for men, women, and children in more than 190 countries worldwide. The brand sponsors major polo events around the world, including the U.S. Open Polo Championship®, held annually at NPC in The Palm Beaches, the premier polo tournament in the United States. Historic deals with ESPN in the United States, TNT and Eurosport in Europe, and Star Sports in India now broadcast several of the premier polo championships in the world, sponsored by U.S. Polo Assn., making the thrilling sport accessible to millions of sports fans globally for the very first time.U.S. Polo Assn. has consistently been named one of the top global sports licensors in the world alongside the NFL, PGA Tour, and Formula 1, according to License Global. In addition, the sport-inspired brand is being recognized internationally with awards for global growth. Due to its tremendous success as a global brand, U.S. Polo Assn. has been featured in Forbes, Fortune, Modern Retail, and GQ as well as on Yahoo Finance and Bloomberg, among many other noteworthy media sources around the world. For more information, visit uspoloassnglobal.com and follow @uspoloassn.USPA Global is a subsidiary of the United States Polo Association (USPA) and manages the multi-billion-dollar sports brand, U.S. Polo Assn. USPA Global also manages the subsidiary, Global Polo, which is the worldwide leader in polo sport content. To learn more, visit globalpolo.com or Global Polo on YouTube.For Additional Information, Contact:Shannon Stilson - VP, Sports Marketing and MediaPhone +001.561.227.6994 - E-mail: sstilson@uspagl.comStacey Kovalsky - VP, Global PR and CommunicationsPhone +001.561.790.8036 - E-mail: skovalsky@uspagl.comSOURCE: U.S. Polo Assn. Copyright 2026 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com

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Vancouver, British Columbia--(ACN Newswire via SeaPRwire.com - March 5, 2026) - Lancaster Resources Inc. (CSE: LCR) (OTC Pink: LANRF) (FSE: 6UF0) ("Lancaster" or the "Company") announces the director resignation of Penny White, effective March 3, 2026. The Board thanks Penny White for her valuable contributions during her tenure and wishes her continued success in her future endeavors.The Company is also pleased to announce the appointment of Mr. Rob Heaslop, as a director to the company's Board of Directors, effective immediately.Mr. Heaslop is a geologist with 20 years' of exploration and resource development experience in Africa, Australia, and the Pacific with specific expertise in project generation and early stage targeting for precious and base metal deposits. Mr. Heaslop holds a Bachelor of Science (Hons) from The University of Queensland majoring in earth science and geology, and during his career has worked for major, junior, and private exploration and mining companies. In 2016, Mr. Heaslop founded his privately owned project generation company, MRG Resources Pty Ltd, that has created significant value identifying exploration opportunities in Australia, including deals with major and mid-tier mining houses and private exploration companies. Mr. Heaslop is a member of the Australasian Institute of Mining and Metallurgy (MAusIMM), Australian Institute of Geoscientists (MAIG), and the Society of Economic Geologists (SEG)."We are thrilled to welcome Mr. Heaslop to the Board," said Andrew Watson, President & CEO of Lancaster Resources. "His technical expertise will be invaluable as Lancaster continues to develop our Lake Cargelligo gold project, Lac Iris polymetallic asset, and our other critical and precious mineral assets."Rob Heaslop commented, "I am focused on the opportunities ahead and committed to help navigate a successful exploration program for our projects and shareholders. I am truly excited to continue working with the team here."The new board appointment reflects Lancaster Resources' transition to a new corporate direction and commitment to strengthening its leadership and strategic capabilities to enhance shareholder value and propel the company's growth in the mining industry.Andrew Watson, P.Eng., President & CEO and a Director of the Company, is a Qualified Person as defined under National Instrument 43-101 – Standards of Disclosure for Mineral Projects. Mr. Watson has reviewed and approved the scientific and technical information contained in this news release. Mr. Watson is a Director and the President and CEO of Lancaster and is not independent of the Company.About Lancaster Resources Inc. Lancaster Resources Inc. is a Canadian exploration company advancing a diversified portfolio of gold and silver exploration projects in established mining jurisdictions. The Company holds a 100% interest in the Lake Cargelligo Gold Project in New South Wales, Australia, which is prospective for both gold and silver mineralization, covering approximately 62,300 hectares with a history of drilling and exploration and multiple high-priority targets. In Canada, Lancaster's assets include the Lac Iris Polymetallic Project in Quebec's James Bay region and the Piney Lake Gold Project in Saskatchewan. Lancaster's portfolio provides exposure to gold, silver, and polymetallic exploration opportunities across tier-one jurisdictions.Andrew Watson, President & Chief Executive Officer,Lancaster Resources Inc.Andrew@Lancaster-Resources.comTel: (604) 923-6100www.lancaster-resources.comThe Canadian Securities Exchange has not reviewed, approved nor disapproved the contents of this news release. Cautionary Statement Regarding Forward-Looking StatementsCertain statements contained in this press release constitute forward-looking information. These statements relate to future events, or Lancaster's future performance. The use of any of the words "could", "expect", "believe", "will", "projected", "estimated" and similar expressions and statements relating to matters that are not historical facts are intended to identify forward-looking information and are based on Lancaster's current belief or assumptions as to the outcome and timing of such future events. Actual future results may differ materially. In particular, the ability of Lancaster to execute its exploration plans, raise capital, retain key personnel, identify, acquire, explore, and develop high-quality mineral-rich properties constitute forward-looking information. Actual results and developments may differ materially from those contemplated by forward-looking information. Readers are cautioned not to place undue reliance on forward-looking information. The statements made in this press release are made as of the date hereof. Lancaster disclaims any intention or obligation to publicly update or revise any forward-looking information, whether as a result of new information, future events or otherwise, except as may be expressly required by applicable securities laws.To view the source version of this press release, please visit https://www.newsfilecorp.com/release/286260 Copyright 2026 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com

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SHENZHEN, CHINA, Mar 5, 2026 - (ACN Newswire via SeaPRwire.com) - China Medical System Holdings Limited (“CMS” or the “Group”) is pleased to announce that self-developed innovative drug INHBE-targeting small nucleic acid drug CMS-D008 injection (“CMS-D008”) received the Drug Clinical Trial Approval Notice issued by National Medical Products Administration (“NMPA”) on 4 March 2026. The NMPA has approved the conduct of clinical trials of CMS-D008 injection for overweight or obese individuals.About CMS-D008CMS-D008 is a novel siRNA therapy administered by subcutaneous injection. CMS-D008 targets and reduces the hepatic expression of the inhibin subunit beta E (INHBE) gene and lowers the level of Activin E protein encoded by INHBE, which blocks Activin E-ALK7 signaling and reduces fat accumulation effectively. Preclinical studies suggested that CMS-D008 efficiently and sustainably suppressed INHBE expression. In the diet-induced obesity model, CMS-D008 enhanced weight loss by reducing fat mass while retaining lean mass with a good safety profile. It demonstrates potentially better prospects for high-quality, long-term weight loss that boosts fat-specific loss while preserving muscle mass. In the future, it may be developed for the treatment of overweight/obesity, abdominal obesity, and related metabolic diseases.Fat Loss, muscle preserved: a potentially better therapeutic option for overweight/obesity Overweight or obesity is a chronic, progressive, relapsing disease characterized by excessive accumulation or abnormal distribution or function of body fat[1]. World Obesity Atlas 2025 Report projected that the global proportion of overweight and obese adults will rise to 50%, with nearly 3 billion adults impacted by high body mass index (BMI), and the population of adults who are overweight or obese in China is projected to reach 515 million by 2030[2]. Existing GLP-1RAs have been proven to be effective for the treatment of overweight and obesity. The main actions of GLP-1RAs are to suppress appetite by acting on the central nervous system and to delay gastric emptying[3]. INHBE’s novel mechanism of action differs from GLP-1RAs. INHBE is identified through genome-wide association studies. Populations with loss of function in INHBE are associated with favorable fat distribution and beneficial metabolic characteristics[4]. Targeted inhibition of INHBE might be more conducive for long-term weight management at the genetic level with precisely lower visceral fat and favorable metabolic profiles.CMS-D008 teams up with CMS-D005: highly effective weight loss plus long-term maintenance, building a more comprehensive weight-loss solutionCMS-D008 will synergize with CMS-D005, a self-developed innovative drug currently in clinical development. CMS-D008 reduces fat without sacrificing muscle mass by precisely inhibiting INHBE gene expression; while CMS-D005, as a GLP-1R/GCGR dual agonist, can effectively reduce liver fat while losing weight. The synergy between these two drugs will achieve highly effective weight loss benefits and long-term maintenance of results, jointly enhancing the Group’s R&D capabilities and product competitiveness in the field of obesity/metabolic treatment. Furthermore, leveraging the Group’s mature network resources in the field of cardiovascular and metabolic diseases, the drug’s R&D and commercialization process will be accelerated, providing patients with more comprehensive and innovative treatment options.The Group is actively preparing to initiate relevant clinical trials and strives to launch the Product as soon as possible.About CMSCMS is a platform company linking pharmaceutical innovation and commercialization with strong product lifecycle management capability, dedicated to providing competitive products and services to meet unmet medical needs.CMS focuses on the global first-in-class (FIC) and best-in-class (BIC) innovative products, and efficiently promotes the clinical research, development and commercialization of innovative products, enabling the continuous transformation of scientific research into clinical practices to benefit patients.CMS deeply engages in several specialty therapeutic fields, and has developed proven commercialization capabilities, extensive networks and expert resources, resulting in leading academic and market positions for its major marketed products. CMS continues to promote the in-depth development in its advantageous specialty fields, strengthening the competitiveness of the cardiovascular-kidney-metabolic/ gastroenterology/ ophthalmology/ skin health businesses, bringing economies of scale in specialty fields. Among them, the skin health business (Dermavon) has become a leading enterprise in its field, and is proposed to be listed independently on the SEHK. Meanwhile, CMS continuously promotes the operation and development of its integrated R&D, manufacturing and commercialization chain in Southeast Asia and the Middle East, capturing growth opportunities in emerging markets to support the high-quality and sustainable development of the Group.Reference:1. Chinese Society of Endocrinology. Guideline for chronic weight management and clinical practice of anti-obesity medications(2024 version). Chinese Journal of Endocrinology and Metabolism. 2024,40(7):545-564.2. World Obesity Federation. World Obesity Atlas 2025. London: World Obesity Federation, 2025. https://data.worldobesity.org/publications/?cat=233. Zhikai Zheng, Yao Zong, Yiyang Ma, Yucheng Tian, Yidan Pang, Changqing Zhang, Junjie Gao. Glucagon-like peptide-1 receptor: mechanisms and advances in therapy. Sig Transduct Target Ther 9, 234 (2024). doi: 10.1038/s41392-024-01931-z4. Parsa Akbari, Olukayode A Sosina, Jonas Bovijn, et al. Multiancestry exome sequencing reveals INHBE mutations associated with favorable fat distribution and protection from diabetes. Nat Commun.2022 Aug 23;13(1):4844. doi: 10.1038/s41467-022-32398-7.CMS Disclaimer and Forward-Looking StatementsThis press release is not intended to promote any products to you and is not for advertising purposes. This press release does not recommend any drugs, medical devices and/or indications. If you want to know more about the diagnosis and treatment of specific diseases, please follow the opinions or guidance of your doctor or other medical and health professionals. Any treatment-related decisions made by healthcare professionals should be based on the patient’s specific circumstances and in accordance with the drug package insert.This press release which has been prepared by CMS does not constitute any offer or invitation to purchase or subscribe for any securities, and shall not form the basis for or be relied on in connection with any contract or binding commitment whatsoever. This press release has been prepared by CMS based on information and data which it considers reliable, but CMS makes no representation or warranty, express or implied, whatsoever, and no reliance shall be placed on, the truth, accuracy, completeness, fairness and reasonableness of the contents of this press release. Certain matters discussed in this press release may contain statements regarding the Group’s market opportunity and business prospects that are individually and collectively forward-looking statements. Such forward-looking statements are not guarantees of future performance and are subject to known and unknown risks, uncertainties and assumptions that are difficult to predict. Any forward-looking statements and projections made by third parties included in this press release are not adopted by the Group and the Company is not responsible for such third-party statements and projections.Media ContactBrand: China Medical System Holdings Ltd.Contact: CMS Investor RelationsEmail: ir@cms.net.cnWebsite: https://web.cms.net.cn/en/home/ Copyright 2026 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com

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